Chelsea is no stranger to controversy, it kind of comes with the territory of being a comedian. Sometimes they make jokes that are a bit over the top and cause a stir amongst those at the other end of the joke. On a recent appearance at the Conan O'Brien show, Handler caused some jaws to drop as she was borderline rude to the red headed host. Isn't there some kind of code among late night hosts, like where they have each other's backs?? Handler throws a low blow at Team Coco as she calls redheads 'ridiculous', and says "I had sex with one redhead one time, and it was very disturbing what I saw." O'Brien responded to the joke playfully with a line about how it looks like it's on fire 'down there', so in the end no feelings were hurt and both comedians delivered some great laughs to the audience. Another star that Handler has made jokes about that weren't so well received were those aimed at Nick Cannon's wife Mariah Carey. Cannon responded to the nasty jokes by puffing his chest out and firing back at Handler via Twitter, but in the end the two called a truce and all was well. During her comedy shows Chelsea has also been caught throwing jabs at Angelina Jolie, since Handler team Anison. Handler defends Aniston endlessly calling Jolie a homewrecker, and other nasty words. Jolie has yet to comment on anything said about her by Handler, and we doubt she ever will. She's probably never even heard the jokes. I guess this just shows that to be a big player in Hollywood you gotta be able to dish it and take it all the same. At the end of the day, Chelsea Handler is a comedian and she will do whatever she has to do to make people laugh.